This paper encompasses the specific problem of how transforming industry clusters in environments prepared to create Virtual Organizations. This kind of coalitions is known as Virtual Organization Breeding Environments (VBEs). In order to reach the envisaged objective a set of guidelines for implementing VBEs has been proposed and its current results have been presented here. These guidelines are strongly based on modeling frameworks. This approach is being tested in a cluster of moulds and dies producers from Brazil. In the future, it is intended to use these guidelines as a structured approach to systematize the implementation of any type of VBE.