Animals Desmin PCR Dystrophie Myotonique Myotonic Dystrophy Type 1 Transgenic mouse Myostatin Myotonic dystrophy Maximal force Central nervous system Aging Glucocorticoid-receptor Brain dysfunction Myotonic Dystrophy Endurance training Glucocorticoids Antisense oligonucleotide DM1 Exercice PacBio Mouse model Cardiac muscle BIOLOGIE MOLECULAIRE Intermediate filament Therapy GABA Antisense oligonucleotides Trinucleotide Repeat Expansion ARN Transgenic mouse model KNOCKOUT MICE Male CONGENITAL MYATHENIC SYNDROME Centronuclear myopathy Fibrosis Expression In vivo Dystrophin AAV Duchenne muscular dystrophy Gene therapy Genotype phenotype correlation Acetylcholinesterase deficiency Cell model Mice Humans Acute coronary syndrome CMS Cell culture model Cytoskeleton Knockout Dystrophie myotonique Thérapie génique Acetylcholinesterase knockout mouse Astrocyte Myelin Oligodendrocytes CTG repeat contractions Myotonic dystrophy type 1 Motoneuron Quantitative microdialysis CTG repeats Mouse models Myotonic dystrophy mouse models Gene editing Myotonic Dystrophy type 1 Cell penetrating peptide Muscle Transcriptomics RNA splicing Skeletal muscle Exercise DMPK Heart failure Long read sequencing RNA interference CRISPR/Cas9 Muscular dystrophy Glutamate CRISPRi RNA biology Brain Dynamin 2 Oligodendrocyte Alternative splicing Glial cells Neuron GSK3␤ Astrocytes ACETYLCHOLINESTERASE MBNL Trinucleotide repeat expansion DMSXL mice Hypoxia Gene Therapy Autophagy Diaphragm Heart CTG repeat instability Dilated cardiomyopathy