Serious games have shown potential as learning material, but are not very engaging. One reason why games are considered to be fun is their ability to provide us with an interesting fantasy world to explore and play in, but this seems at odds with the more serious nature of formal training. In this study, a two by two (familiar versus unfamiliar visual setting and familiar versus unfamiliar story setting) single-blind experiment (N=60) was performed, testing the effect of the familiarity of aesthetics on game experience and learning. Significant effects of story condition on learning and game experience was found, with a familiar story setting leading to better learning, but subdued game experience. Other effects were not significant.