In this paper, the scheme that combines a prefilter for sidelobe minimization with the time-reversal prefilter in the ultra wide band wireless communication system is proposed. The proposed scheme can be used in the variable symbol interval situation. When the system has the symbol interval which is larger than one-tap, the proposed scheme exploits the symbol interval to minimize the ISI. In the multi user environment, the proposed scheme is combined with space-time multiplexing scheme to alleviate multi user interference (MUI). Through numerical simulations, we examine the bit error rate (BER) performance of the proposed scheme in single user and two-user environment, and show that the proposed scheme can offer some BER performance gains comparing to the conventional TR scheme.