This paper introduces Purenet, which is a self-learning malware detection system aimed at avoiding zero-day attacks and other delays in patching application systems when attacks are identified. The concept and architecture of Purenet are described, specifically positioning anomaly detection as the system enabler. Deployment of the system in an operational environment is discussed, and associated recommendations and findings are presented based on this. Findings from the prototype include various considerations which should influence the design of such security software including latency considerations, multi protocol support, cloud anti-malware integration, resource requirement issues, reporting, base platform hardening and SIEM integration.