The manufacturing execution systems (MES) is one of the key elements consisting smart factory. It is responsible for shop floor control by performing managing resources, dispatching production orders, executing production orders, collecting production data, analyzing production performances, and so on. Through these functionalities, the MES aims high productivity. The dispatching in the MES helps these aims. The selection of job in manufacturing execution systems (MES) is performed by dispatching rule. The dispatching rule is composed of several factors affecting scheduling objective and constraint. In most cases, the dispatching rule is expressed as the weighted sum of factors and the weight moderates the relative importance among factors. To find optimal weight configuration requires heavy calculation burden so that it cannot adapt dynamic order changes. To solve this problem, one of machine learning algorithms is used in this study. The multi-layer perceptron learns the best weight configuration according to orders and predict the best weight configuration for new orders. The proposed method is tested by field data and proved its usefulness.