Since its emergence, Cloud Computing (CC) has revolutionized organization through offering them a large range of easily accessible, scalable, and non-expensive services. As CC has been gaining popularity, it has an impact on the strategic and operational level of every organization. Thus, wondering about its impact on the organizational strategic alignment is a must. This study develops the Cloud Computing framework of Strategic Alignment Model, where strategic fit between operational and strategic levels in organization is achieved through cloud-enabled multiple iterative processes. The study aims to understand whether cloud computing increases operational and strategic efficiencies of organization and if yes then how. After presenting the theoretical background, the hypotheses, and the built cloud framework, we discuss the way strategic alignment theory helps us to better understand how information flows within the strategic fit of business and IT and what is the role of CC in it. This study addresses the strategic alignment as well as the cloud computing literature.