Information and Communication Technologies (ICTs) play a pivotal role in enhancing learning and teaching at all levels of education across the globe. Many developed countries appreciate that the use of ICTs has improved the quality of education. Developing countries such as Malawi have also incorporated ICTs in various curricula of programmes at all levels of education. Unfortunately, these resource constrained countries face a number of challenges in gleaning the maximum benefits of ICT in education sector.This paper discusses the fundamental challenges underlying ICT development in the education system in Malawi. Some recommendations have also been made on how to mitigate the challenges that are encountered in the education sector in Malawi. The paper further advances the notion that the ICT intervention in education can be meaningful and effective if all stakeholders such as government, private sector, policy and decision makers, communities, students, teachers and international agencies are engaged at all levels of the education system. An attempt has also been made to compare different models of implementing ICT in the education system in a resource constrained environment. The paper finally proposes an inclusive model for the ICT intervention in education system in Malawi.