Nowadays, a mechatronic system is regarded as a synergistic integration of a wide range of disciplines (electrical/electronic, mechanical, software). Therefore, an integration of numerous technical disciplines and expertises is often required during the design process of mechatronic systems. However, neither academia nor industry has yet provided fully effective solutions to help the engineers achieve such multidisciplinary integration. Multidisciplinary interface modelling approach is considered as an effective way to represent the interaction between the boundaries of components of different disciplines. The authors propose a new multidisciplinary interface modelling approach to address the issue of multidisciplinary integration. A three dimensional (3D) measurement system, considered as an opto-mechatronic system integrating synergistically the electrical/electronic system, mechanical parts and information processing and optical technology is used to demonstrate the multidisciplinary interface modelling approach. A demonstrator based on the proposed approach has been developed by using CATIA System Engineering V6.