The identification and prioritization of locations that have potential for failure (also referred to as thickness measurement locations (TMLs)) in the in-service inspection planning of offshore topside piping equipment requires a significant amount of data analysis together with relevant information. In this context, planning personnel analyze data and information retrieved from piping inspection databases through enterprise resource planning (ERP) software to investigate possible degradation trends in order to recognize the TMLs that have reached a critical level. It is observed that suboptimal prioritization occurs due to time restriction vs. amount of data and/or information that has to be evaluated. The suboptimal prioritization omits some of the critical TMLs, increasing the risk of failures whilst also increasing cost due to taking non-critical TMLs into inspection. Therefore, this manuscript illustrates an approach to integrate the decision support modules (DSMs) via an artificial neural network model for the optimum prioritization.