Feedback is a fundamental concept in automatic control. Feedback loops are used extensively in industrial applications today and there are work-procedures for designing traditional single parameter control loops. In the work procedure it is important to select control-parameters, manipulated parameters and control-strategies. A similar work-procedure could also be used for designing plant-wide control feedback loops. Key performance Indicators is thus an important concept since they can be used as control-parameters. In this paper an analogy between the single-loop and plant-wide approach is discussed, and key performance indicators from the new international standard ISO 22400 are presented.