Osteoporotic hip fractures have a significant morbidity and excess mortality among the elderly and have imposed huge health and economic burdens on societies worldwide. A medical database of 349 patients that have been operated for hip fracture has been analyzed. Two models of data were used in Multi-Layer Perceptrons, Radial Basis Function and Naïve Bayes networks, in order to predict the 30-day mortality after a hip fracture surgery and also to investigate which is the most appropriate risk factor between the New Mobility Score and Institution factor for the Greek population. The proposed method may be used as a screening tool that will assist orthopedics in the surgery of the hip fracture according to each different patient.