This cross-national study evaluates the contingency of the relationship between ICT initiatives and public health outcomes on (1) education; (2) macro-economic stability and; (3) institutions. Resource Based View’s resource complementary perspective and literature on Information and Communication Technology and delivery of public health are used as the guiding theoretical framework. Publicly accessible archived data from more than 150 nations are collected to comprehend the interaction effect. Delivery of public health outcomes is measured through mortality rate (adult), availability of sanitation facilities, incidence of TB and under nourishment. The results indicated that ICT initiatives interact with above three contingencies affecting public health outcomes. Education level positively moderated the relationship between ICT and public health outcomes. Institutions moderated the relationship of ICT and public health outcomes in a positive direction. The moderating effect is measured using PLS. Implications of the findings for theoretical discourse of the resource complimentary perspective and future research are discussed.