HINT-KB: The Human Interactome Knowledge Base - Artificial Intelligence Applications and Innovations - Part II (AIAI 2012) Access content directly
Conference Papers Year : 2012

HINT-KB: The Human Interactome Knowledge Base


Proteins and their interactions are considered to play a significant role in many cellular processes. The identification of Protein-Protein interactions (PPIs) in human is an open research area. Many Databases, which contain information about experimentally and computationally detected human PPIs as well as their corresponding annotation data, have been developed. However, these databases contain many false positive interactions, are partial and only a few of them incorporate data from various sources. To overcome these limitations, we have developed HINT-KB ( which is a knowledge base that integrates data from various sources, provides a user-friendly interface for their retrieval, estimates a set of features of interest and computes a confidence score for every candidate protein interaction using a modern computational hybrid methodology.
Fichier principal
Vignette du fichier
978-3-642-33412-2_63_Chapter.pdf (394.29 Ko) Télécharger le fichier
Origin : Files produced by the author(s)

Dates and versions

hal-01523049 , version 1 (16-05-2017)


Attribution - CC BY 4.0



Konstantinos Theofilatos, Christos Dimitrakopoulos, Dimitrios Kleftogiannis, Charalampos Moschopoulos, Stergios Papadimitriou, et al.. HINT-KB: The Human Interactome Knowledge Base. 8th International Conference on Artificial Intelligence Applications and Innovations (AIAI), Sep 2012, Halkidiki, Greece. pp.612-621, ⟨10.1007/978-3-642-33412-2_63⟩. ⟨hal-01523049⟩
293 View
58 Download



Gmail Facebook Twitter LinkedIn More