Intelligent Transportation Systems (ITS) are technologies for efficient traffic management, e.g. accident and congestion prevention, reduced emissions, traveler information etc. Despite the potential benefits identified by previous research, there is a remarkable lack of a robust e-Business case for ITS. Although the necessary technology exists and the internet provides opportunities for more cost effective integration of systems and services, many ITS are not sustainable and great ideas do not develop further. Many applications are still too expensive to purchase and install, they require substantial upfront investments and the returns will take many years to materialize. This paper emphasizes the need for ITS to take advantage of the developments in Information and Communication Technologies (ICTs) and the internet, and proposes some e-Business model framework for ITS. We also address sustainability issues and aspects of the network economy for ITS companies. Finally, we present a stakeholders’ analysis and a future research agenda.